Swelling after Tramadol in dogs

The FDA has received 258 reports of swelling in dogs after Tramadol. That is 6.8% of all reports for this medicine, compared with 2.8% across reports for all dog medicines, so it is reported unusually often with this medicine.

258Reports
63%Marked serious
17%Recovered
23%Died or euthanised
5 daysTypical onset
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How soon it started

Same day
37 17%
1–2 days
40 19%
3–7 days
42 20%
1–4 weeks
48 23%
Over a month
46 22%

How the animals did

Recovered
42 16%
Recovered with lasting effects
2 0.8%
Still unwell when reported
116 45%
Died
16 6.2%
Euthanised
44 17%
Not known
38 15%

Problems reported at the same time

Age of the animals

Under 1 year
9
1–3 years
48
4–7 years
85
8–11 years
87
12+ years
27

About this medicine

Type: medicine.

Questions owners ask

Can Tramadol cause swelling in dogs?
258 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 5 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Swelling with similar medicines

All reported side effects of Tramadol in dogs · Medicines most reported with swelling