Didn't work as expected after Polysulfated Glycosaminoglycan in dogs

The FDA has received 698 reports of didn't work as expected in dogs after Polysulfated Glycosaminoglycan. That is 13% of all reports for this medicine, compared with 13% across reports for all dog medicines.

698Reports

21%Marked serious

6.4%Recovered

5.0%Died or euthanised

42 daysTypical onset

How soon it started

Same day

107 24%

1–2 days

5 1.1%

3–7 days

14 3.1%

1–4 weeks

67 15%

Over a month

255 57%

How the animals did

Recovered

36 5.2%

Recovered with lasting effects

9 1.3%

Still unwell when reported

114 16%

Died

12 1.7%

Euthanised

23 3.3%

Not known

504 72%

Problems reported at the same time

54 7.7%

45 6.4%

39 5.6%

38 5.4%

35 5.0%

33 4.7%

Product defect, general

27 3.9%

Weakness

24 3.4%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

260

12+ years

276

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause didn't work as expected in dogs?: 698 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 42 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

Didn't work as expected after Melarsomine (Immiticide) 646 reports · 2.8% of its reports
Didn't work as expected after Diphenhydramine 585 reports · 12% of its reports
Didn't work as expected after Butorphanol 1,022 reports · 23% of its reports
Didn't work as expected after Cefpodoxime 671 reports · 17% of its reports
Didn't work as expected after Tramadol 475 reports · 13% of its reports
Didn't work as expected after Florfenicol + Mometasone + Terbinafine 969 reports · 27% of its reports
Didn't work as expected after Desoxycorticosterone Pivalate 355 reports · 11% of its reports
Didn't work as expected after Propofol 600 reports · 20% of its reports
Didn't work as expected after Dirlotapide 712 reports · 25% of its reports
Didn't work as expected after Isoflurane 474 reports · 17% of its reports

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with didn't work as expected