Didn't work as expected after Propofol in dogs

600 reports to the FDA describe didn't work as expected in dogs given Propofol. That is 20% of all reports for this medicine, compared with 13% across reports for all dog medicines, so it is reported unusually often with this medicine.

600Reports

42%Marked serious

36%Recovered

6.0%Died or euthanised

Same dayTypical onset

How soon it started

Same day

235 75%

1–2 days

30 9.6%

3–7 days

17 5.4%

1–4 weeks

16 5.1%

Over a month

15 4.8%

How the animals did

Recovered

216 36%

Recovered with lasting effects

1 0.2%

Still unwell when reported

43 7.2%

Died

16 2.7%

Euthanised

20 3.3%

Not known

304 51%

Problems reported at the same time

35 5.8%

34 5.7%

33 5.5%

32 5.3%

Injection site reaction

31 5.2%

Breathing problems

30 5.0%

Death

27 4.5%

Hyperexcitation

19 3.2%

Age of the animals

Under 1 year

1–3 years

4–7 years

123

8–11 years

103

12+ years

About this medicine

Type: medicine.

Questions owners ask

Can Propofol cause didn't work as expected in dogs?: 600 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

Didn't work as expected after Melarsomine (Immiticide) 646 reports · 2.8% of its reports
Didn't work as expected after Polysulfated Glycosaminoglycan 698 reports · 13% of its reports
Didn't work as expected after Diphenhydramine 585 reports · 12% of its reports
Didn't work as expected after Butorphanol 1,022 reports · 23% of its reports
Didn't work as expected after Cefpodoxime 671 reports · 17% of its reports
Didn't work as expected after Tramadol 475 reports · 13% of its reports
Didn't work as expected after Florfenicol + Mometasone + Terbinafine 969 reports · 27% of its reports
Didn't work as expected after Desoxycorticosterone Pivalate 355 reports · 11% of its reports
Didn't work as expected after Dirlotapide 712 reports · 25% of its reports
Didn't work as expected after Isoflurane 474 reports · 17% of its reports

All reported side effects of Propofol in dogs · Medicines most reported with didn't work as expected