Seizures after Polysulfated Glycosaminoglycan in dogs

The FDA has received 196 reports of seizures in dogs after Polysulfated Glycosaminoglycan. That is 3.6% of all reports for this medicine, compared with 4.4% across reports for all dog medicines.

196Reports
64%Marked serious
32%Recovered
26%Died or euthanised
21 daysTypical onset
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How soon it started

Same day
20 19%
1–2 days
13 12%
3–7 days
7 6.6%
1–4 weeks
20 19%
Over a month
46 43%

How the animals did

Recovered
58 30%
Recovered with lasting effects
4 2.0%
Still unwell when reported
27 14%
Died
24 12%
Euthanised
26 13%
Not known
57 29%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
8
4–7 years
23
8–11 years
64
12+ years
95

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause seizures in dogs?
196 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 21 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Seizures with similar medicines

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with seizures