Seizures after Propofol in dogs

The FDA has received 307 reports of seizures in dogs after Propofol. That is 10.0% of all reports for this medicine, compared with 4.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

307Reports
63%Marked serious
27%Recovered
30%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
127 67%
1–2 days
29 15%
3–7 days
8 4.2%
1–4 weeks
12 6.3%
Over a month
14 7.4%

How the animals did

Recovered
82 27%
Recovered with lasting effects
1 0.3%
Still unwell when reported
41 13%
Died
65 21%
Euthanised
27 8.8%
Not known
91 30%

Problems reported at the same time

88 29%
48 16%
31 10%
21 6.8%
21 6.8%
20 6.5%

Age of the animals

Under 1 year
29
1–3 years
59
4–7 years
106
8–11 years
60
12+ years
22

About this medicine

Type: medicine.

Questions owners ask

Can Propofol cause seizures in dogs?
307 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Seizures with similar medicines

All reported side effects of Propofol in dogs · Medicines most reported with seizures