Seizures after Melarsomine (Immiticide) in dogs

The FDA has received 446 reports of seizures in dogs after Melarsomine. That is 2.0% of all reports for this medicine, compared with 4.4% across reports for all dog medicines, so it is reported less often than average with this medicine.

446Reports
52%Marked serious
17%Recovered
16%Died or euthanised
8 daysTypical onset
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How soon it started

Same day
50 20%
1–2 days
38 15%
3–7 days
37 15%
1–4 weeks
61 24%
Over a month
67 26%

How the animals did

Recovered
74 17%
Recovered with lasting effects
2 0.4%
Still unwell when reported
62 14%
Died
53 12%
Euthanised
20 4.5%
Not known
235 53%

Problems reported at the same time

Age of the animals

Under 1 year
7
1–3 years
176
4–7 years
172
8–11 years
65
12+ years
8

About this medicine

Melarsomine treats adult heartworm infection (a series of injections given by a vet).

Products with this ingredient include Immiticide, Diroban. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Melarsomine cause seizures in dogs?
446 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 8 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Seizures with similar medicines

All reported side effects of Melarsomine in dogs · Medicines most reported with seizures