Seizures after Butorphanol in dogs

The FDA has received 335 reports of seizures in dogs after Butorphanol. That is 7.5% of all reports for this medicine, compared with 4.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

335Reports
80%Marked serious
46%Recovered
22%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
203 74%
1–2 days
20 7.3%
3–7 days
17 6.2%
1–4 weeks
21 7.6%
Over a month
14 5.1%

How the animals did

Recovered
153 46%
Recovered with lasting effects
1 0.3%
Still unwell when reported
58 17%
Died
49 15%
Euthanised
24 7.2%
Not known
50 15%

Problems reported at the same time

70 21%
37 11%
33 9.9%
25 7.5%
24 7.2%
24 7.2%

Age of the animals

Under 1 year
29
1–3 years
52
4–7 years
107
8–11 years
90
12+ years
39

About this medicine

Type: medicine.

Questions owners ask

Can Butorphanol cause seizures in dogs?
335 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Seizures with similar medicines

All reported side effects of Butorphanol in dogs · Medicines most reported with seizures