Leptospirosis Vaccine side effects in dogs

8,017 reports sent to the FDA between 2011 and 2026 involve Leptospirosis Vaccine in dogs. The most reported problems were vomiting, lethargy, allergic reaction. 54% were marked serious, and where it was recorded, signs eased after stopping the medicine in 43% of cases.

8,017Reports
54%Marked serious
0.0%Only medicine involved
33%Recovered
9.7%Died or euthanised
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About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Most reported side effects

3,265 41%
1,929 24%
1,593 20%
1,153 14%
524 6.5%
512 6.4%
404 5.0%

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't stop fleas
11 0.1%

How soon problems started

Same day
3,232 48%
1–2 days
881 13%
3–7 days
513 7.7%
1–4 weeks
757 11%
Over a month
1,307 20%

Time from the first dose to the first sign, where both dates were reported (6,690 reports).

How the animals did

Recovered
2,603 32%
Recovered with lasting effects
36 0.4%
Still unwell when reported
2,893 36%
Died
405 5.1%
Euthanised
371 4.6%
Not known
1,709 21%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other vaccines for dogs