Allergic reaction after Leptospirosis Vaccine in dogs

1,683 reports to the FDA describe allergic reaction in dogs given Leptospirosis Vaccine. That is 21% of all reports for this medicine, compared with 2.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

1,683Reports
74%Marked serious
50%Recovered
3.9%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
1,350 85%
1–2 days
89 5.6%
3–7 days
21 1.3%
1–4 weeks
60 3.8%
Over a month
77 4.8%

How the animals did

Recovered
846 50%
Recovered with lasting effects
2 0.1%
Still unwell when reported
667 40%
Died
45 2.7%
Euthanised
20 1.2%
Not known
103 6.1%

Problems reported at the same time

Age of the animals

Under 1 year
139
1–3 years
928
4–7 years
401
8–11 years
154
12+ years
53

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause allergic reaction in dogs?
1,683 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Allergic reaction with similar medicines

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with allergic reaction