Itching after Leptospirosis Vaccine in dogs

The FDA has received 524 reports of itching in dogs after Leptospirosis Vaccine. That is 6.5% of all reports for this medicine, compared with 4.3% across reports for all dog medicines, so it is reported unusually often with this medicine.

524Reports
56%Marked serious
37%Recovered
4.6%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
267 56%
1–2 days
71 15%
3–7 days
26 5.5%
1–4 weeks
51 11%
Over a month
61 13%

How the animals did

Recovered
185 35%
Recovered with lasting effects
8 1.5%
Still unwell when reported
218 42%
Died
9 1.7%
Euthanised
15 2.9%
Not known
89 17%

Problems reported at the same time

Age of the animals

Under 1 year
63
1–3 years
223
4–7 years
129
8–11 years
72
12+ years
33

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause itching in dogs?
524 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Itching with similar medicines

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with itching