Breathing problems after Leptospirosis Vaccine in dogs

The FDA has received 666 reports of breathing problems in dogs after Leptospirosis Vaccine. That is 8.3% of all reports for this medicine, compared with 2.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

666Reports
84%Marked serious
33%Recovered
23%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
368 62%
1–2 days
59 10%
3–7 days
31 5.3%
1–4 weeks
54 9.2%
Over a month
77 13%

How the animals did

Recovered
218 33%
Recovered with lasting effects
3 0.5%
Still unwell when reported
236 35%
Died
91 14%
Euthanised
60 9.0%
Not known
58 8.7%

Problems reported at the same time

308 46%
251 38%
155 23%
151 23%
125 19%

Age of the animals

Under 1 year
52
1–3 years
224
4–7 years
177
8–11 years
131
12+ years
76

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause breathing problems in dogs?
666 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Breathing problems with similar medicines

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with breathing problems