Fever after Leptospirosis Vaccine in dogs

The FDA has received 512 reports of fever in dogs after Leptospirosis Vaccine. That is 6.4% of all reports for this medicine, compared with 1.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

512Reports

74%Marked serious

27%Recovered

16%Died or euthanised

Same dayTypical onset

How soon it started

Same day

230 50%

1–2 days

66 14%

3–7 days

48 11%

1–4 weeks

46 10%

Over a month

67 15%

How the animals did

Recovered

139 27%

Still unwell when reported

242 47%

Died

38 7.4%

Euthanised

45 8.8%

Not known

48 9.4%

Problems reported at the same time

263 51%

243 47%

198 39%

132 26%

125 24%

125 24%

118 23%

103 20%

Age of the animals

Under 1 year

1–3 years

167

4–7 years

147

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause fever in dogs?: 512 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within the same day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Fever with similar medicines

Fever after Rabies Vaccine 585 reports · 5.9% of its reports
Fever after Bordetella Vaccine 548 reports · 5.8% of its reports
Fever after Lyme Vaccine 173 reports · 2.5% of its reports
Fever after Distemper-parvo Vaccine 409 reports · 6.3% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with fever