Loss of appetite after Leptospirosis Vaccine in dogs

The FDA has received 1,329 reports of loss of appetite in dogs after Leptospirosis Vaccine. That is 17% of all reports for this medicine, compared with 8.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

1,329Reports
69%Marked serious
18%Recovered
23%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
324 29%
1–2 days
239 22%
3–7 days
145 13%
1–4 weeks
181 16%
Over a month
216 20%

How the animals did

Recovered
233 18%
Recovered with lasting effects
5 0.4%
Still unwell when reported
610 46%
Died
125 9.4%
Euthanised
179 13%
Not known
177 13%

Problems reported at the same time

810 61%
688 52%
374 28%
303 23%
198 15%

Age of the animals

Under 1 year
160
1–3 years
286
4–7 years
390
8–11 years
322
12+ years
155

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause loss of appetite in dogs?
1,329 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Loss of appetite with similar medicines

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with loss of appetite