Kidney problems after Leptospirosis Vaccine in dogs

393 reports to the FDA describe kidney problems in dogs given Leptospirosis Vaccine. That is 4.9% of all reports for this medicine, compared with 2.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

393Reports
82%Marked serious
4.8%Recovered
40%Died or euthanised
6 daysTypical onset
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How soon it started

Same day
63 22%
1–2 days
47 17%
3–7 days
38 13%
1–4 weeks
56 20%
Over a month
80 28%

How the animals did

Recovered
19 4.8%
Still unwell when reported
166 42%
Died
47 12%
Euthanised
109 28%
Not known
52 13%

Problems reported at the same time

Age of the animals

Under 1 year
40
1–3 years
55
4–7 years
98
8–11 years
113
12+ years
85

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause kidney problems in dogs?
393 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 6 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Kidney problems with similar medicines

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with kidney problems