Death after Leptospirosis Vaccine in dogs

757 reports to the FDA describe death in dogs given Leptospirosis Vaccine. That is 9.4% of all reports for this medicine, compared with 5.2% across reports for all dog medicines, so it is reported unusually often with this medicine.

757Reports

100%Marked serious

0.0%Recovered

100%Died or euthanised

5 daysTypical onset

How soon it started

Same day

161 25%

1–2 days

111 17%

3–7 days

84 13%

1–4 weeks

124 20%

Over a month

155 24%

How the animals did

Still unwell when reported

1 0.1%

Died

386 51%

Euthanised

369 49%

Not known

1 0.1%

Problems reported at the same time

306 40%

303 40%

298 39%

217 29%

167 22%

156 21%

151 20%

143 19%

Age of the animals

Under 1 year

102

1–3 years

4–7 years

176

8–11 years

241

12+ years

138

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause death in dogs?: 757 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 5 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Death with similar medicines

Death after Rabies Vaccine 952 reports · 9.6% of its reports
Death after Bordetella Vaccine 834 reports · 8.9% of its reports
Death after Lyme Vaccine 209 reports · 3.0% of its reports
Death after Distemper-parvo Vaccine 691 reports · 11% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with death