Diarrhea after Leptospirosis Vaccine in dogs

1,153 reports to the FDA describe diarrhea in dogs given Leptospirosis Vaccine. That is 14% of all reports for this medicine, compared with 8.4% across reports for all dog medicines, so it is reported unusually often with this medicine.

1,153Reports
65%Marked serious
28%Recovered
13%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
482 47%
1–2 days
196 19%
3–7 days
87 8.4%
1–4 weeks
113 11%
Over a month
155 15%

How the animals did

Recovered
326 28%
Recovered with lasting effects
1 0.1%
Still unwell when reported
521 45%
Died
73 6.3%
Euthanised
72 6.2%
Not known
160 14%

Problems reported at the same time

Age of the animals

Under 1 year
227
1–3 years
378
4–7 years
272
8–11 years
185
12+ years
79

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause diarrhea in dogs?
1,153 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Diarrhea with similar medicines

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with diarrhea