Swelling after Leptospirosis Vaccine in dogs

1,593 reports to the FDA describe swelling in dogs given Leptospirosis Vaccine. That is 20% of all reports for this medicine, compared with 2.8% across reports for all dog medicines, so it is reported unusually often with this medicine.

1,593Reports
57%Marked serious
44%Recovered
3.6%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
1,053 71%
1–2 days
127 8.6%
3–7 days
66 4.4%
1–4 weeks
105 7.1%
Over a month
133 9.0%

How the animals did

Recovered
706 44%
Still unwell when reported
685 43%
Died
29 1.8%
Euthanised
29 1.8%
Not known
144 9.0%

Problems reported at the same time

Age of the animals

Under 1 year
227
1–3 years
752
4–7 years
399
8–11 years
154
12+ years
51

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause swelling in dogs?
1,593 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Swelling with similar medicines

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with swelling