Injection site reaction after Leptospirosis Vaccine in dogs

394 reports to the FDA describe injection site reaction in dogs given Leptospirosis Vaccine. That is 4.9% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

394Reports
35%Marked serious
25%Recovered
5.1%Died or euthanised
6 daysTypical onset
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How soon it started

Same day
80 24%
1–2 days
54 16%
3–7 days
53 16%
1–4 weeks
67 20%
Over a month
77 23%

How the animals did

Recovered
100 25%
Still unwell when reported
210 53%
Died
10 2.5%
Euthanised
10 2.5%
Not known
64 16%

Problems reported at the same time

146 37%
114 29%
62 16%
46 12%
39 9.9%
39 9.9%

Age of the animals

Under 1 year
70
1–3 years
101
4–7 years
107
8–11 years
71
12+ years
41

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause injection site reaction in dogs?
394 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 6 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Injection site reaction with similar medicines

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with injection site reaction