Injection site reaction after Rabies Vaccine in dogs

The FDA has received 342 reports of injection site reaction in dogs after Rabies Vaccine. That is 3.5% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

342Reports
40%Marked serious
23%Recovered
6.1%Died or euthanised
8 daysTypical onset
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How soon it started

Same day
63 22%
1–2 days
34 12%
3–7 days
37 13%
1–4 weeks
75 26%
Over a month
79 27%

How the animals did

Recovered
76 22%
Recovered with lasting effects
1 0.3%
Still unwell when reported
149 44%
Died
8 2.3%
Euthanised
13 3.8%
Not known
95 28%

Problems reported at the same time

Swelling
102 30%
Lethargy
86 25%
Loss of appetite
74 22%
Vomiting
46 13%
Fever
38 11%
Diarrhea
35 10%
Hair loss
33 9.6%
Abnormal cytology
31 9.1%

Age of the animals

Under 1 year
63
1–3 years
90
4–7 years
93
8–11 years
64
12+ years
30

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Rabies Vaccine cause injection site reaction in dogs?
342 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 8 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Injection site reaction with similar medicines

All reported side effects of Rabies Vaccine in dogs · Medicines most reported with injection site reaction