Blood problems after Leptospirosis Vaccine in dogs

498 reports to the FDA describe blood problems in dogs given Leptospirosis Vaccine. That is 6.2% of all reports for this medicine, compared with 1.8% across reports for all dog medicines, so it is reported unusually often with this medicine.

498Reports
88%Marked serious
6.8%Recovered
34%Died or euthanised
12 daysTypical onset
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How soon it started

Same day
74 18%
1–2 days
61 14%
3–7 days
50 12%
1–4 weeks
112 27%
Over a month
124 29%

How the animals did

Recovered
33 6.6%
Recovered with lasting effects
1 0.2%
Still unwell when reported
248 50%
Died
57 11%
Euthanised
110 22%
Not known
49 9.8%

Problems reported at the same time

Age of the animals

Under 1 year
67
1–3 years
89
4–7 years
138
8–11 years
147
12+ years
54

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause blood problems in dogs?
498 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 12 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood problems with similar medicines

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with blood problems