Seizures after Leptospirosis Vaccine in dogs

The FDA has received 404 reports of seizures in dogs after Leptospirosis Vaccine. That is 5.0% of all reports for this medicine, compared with 4.4% across reports for all dog medicines.

404Reports

95%Marked serious

25%Recovered

26%Died or euthanised

2 daysTypical onset

How soon it started

Same day

98 27%

1–2 days

88 24%

3–7 days

41 11%

1–4 weeks

79 22%

Over a month

54 15%

How the animals did

Recovered

96 24%

Recovered with lasting effects

3 0.7%

Still unwell when reported

157 39%

Died

59 15%

Euthanised

46 11%

Not known

43 11%

Problems reported at the same time

103 25%

83 21%

72 18%

59 15%

47 12%

45 11%

39 9.7%

34 8.4%

Age of the animals

Under 1 year

1–3 years

4–7 years

106

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause seizures in dogs?: 404 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 2 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Seizures with similar medicines

Seizures after Rabies Vaccine 609 reports · 6.1% of its reports
Seizures after Bordetella Vaccine 517 reports · 5.5% of its reports
Seizures after Lyme Vaccine 115 reports · 1.6% of its reports
Seizures after Distemper-parvo Vaccine 420 reports · 6.5% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with seizures