Tremors after Leptospirosis Vaccine in dogs

The FDA has received 378 reports of tremors in dogs after Leptospirosis Vaccine. That is 4.7% of all reports for this medicine, compared with 3.4% across reports for all dog medicines.

378Reports

60%Marked serious

33%Recovered

11%Died or euthanised

1 daysTypical onset

How soon it started

Same day

136 40%

1–2 days

76 23%

3–7 days

41 12%

1–4 weeks

39 12%

Over a month

45 13%

How the animals did

Recovered

120 32%

Recovered with lasting effects

3 0.8%

Still unwell when reported

164 43%

Died

14 3.7%

Euthanised

27 7.1%

Not known

50 13%

Problems reported at the same time

157 42%

125 33%

111 29%

61 16%

55 15%

49 13%

48 13%

47 12%

Age of the animals

Under 1 year

1–3 years

106

4–7 years

8–11 years

12+ years

About this medicine

Type: vaccine.

Mild, short-lived lethargy, soreness or a small lump at the injection site are the most commonly reported vaccine reactions.

Questions owners ask

Can Leptospirosis Vaccine cause tremors in dogs?: 378 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Tremors with similar medicines

Tremors after Rabies Vaccine 529 reports · 5.3% of its reports
Tremors after Bordetella Vaccine 491 reports · 5.2% of its reports
Tremors after Lyme Vaccine 134 reports · 1.9% of its reports
Tremors after Distemper-parvo Vaccine 332 reports · 5.1% of its reports

All reported side effects of Leptospirosis Vaccine in dogs · Medicines most reported with tremors