Emodepside + Praziquantel (Profender) side effects in cats

5,730 reports sent to the FDA between 2007 and 2026 involve Emodepside + Praziquantel in cats. The most reported problems were hair loss, drooling, application site reaction. 48% were marked serious, and where it was recorded, signs eased after stopping the medicine in 100% of cases.

5,730Reports
48%Marked serious
74%Only medicine involved
28%Recovered
4.9%Died or euthanised
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About this medicine

Emodepside treats intestinal worms (spot-on for cats). Praziquantel treats tapeworms.

Products with this combination include Profender. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Most reported side effects

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a cat still getting fleas or heartworm), not about a side effect.

Didn't prevent heartworm
3 0.1%

How soon problems started

Same day
1,793 41%
1–2 days
1,248 29%
3–7 days
604 14%
1–4 weeks
479 11%
Over a month
230 5.3%

Time from the first dose to the first sign, where both dates were reported (4,354 reports).

How the animals did

Recovered
1,596 28%
Recovered with lasting effects
8 0.1%
Still unwell when reported
376 6.6%
Died
188 3.3%
Euthanised
95 1.7%
Not known
3,467 61%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other dewormers for cats