Diarrhea after Emodepside + Praziquantel (Profender) in cats

238 reports to the FDA describe diarrhea in cats given Emodepside + Praziquantel. That is 4.2% of all reports for this medicine, compared with 5.1% across reports for all cat medicines.

238Reports
58%Marked serious
32%Recovered
7.1%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
71 38%
1–2 days
60 32%
3–7 days
26 14%
1–4 weeks
20 11%
Over a month
8 4.3%

How the animals did

Recovered
76 32%
Still unwell when reported
17 7.1%
Died
10 4.2%
Euthanised
7 2.9%
Not known
128 54%

Problems reported at the same time

Age of the animals

Under 1 year
74
1–3 years
62
4–7 years
30
8–11 years
24
12+ years
26

About this medicine

Emodepside treats intestinal worms (spot-on for cats). Praziquantel treats tapeworms.

Products with this combination include Profender. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Emodepside + Praziquantel cause diarrhea in cats?
238 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Diarrhea with similar medicines

All reported side effects of Emodepside + Praziquantel in cats · Medicines most reported with diarrhea