Death after Emodepside + Praziquantel (Profender) in cats

270 reports to the FDA describe death in cats given Emodepside + Praziquantel. That is 4.7% of all reports for this medicine, compared with 8.9% across reports for all cat medicines, so it is reported less often than average with this medicine.

270Reports

83%Marked serious

0.0%Recovered

100%Died or euthanised

1 daysTypical onset

How soon it started

Same day

68 33%

1–2 days

69 33%

3–7 days

28 14%

1–4 weeks

31 15%

Over a month

10 4.9%

How the animals did

Died

175 65%

Euthanised

94 35%

Not known

1 0.4%

Problems reported at the same time

92 34%

80 30%

40 15%

38 14%

36 13%

31 11%

30 11%

28 10%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Emodepside treats intestinal worms (spot-on for cats). Praziquantel treats tapeworms.

Products with this combination include Profender. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Emodepside + Praziquantel cause death in cats?: 270 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Death with similar medicines

Death after Praziquantel 101 reports · 6.1% of its reports
Death after Praziquantel + Pyrantel 81 reports · 6.4% of its reports
Death after Pyrantel 110 reports · 20% of its reports
Death after Fenbendazole 60 reports · 21% of its reports

All reported side effects of Emodepside + Praziquantel in cats · Medicines most reported with death