Vomiting after Emodepside + Praziquantel (Profender) in cats

801 reports to the FDA describe vomiting in cats given Emodepside + Praziquantel. That is 14% of all reports for this medicine, compared with 18% across reports for all cat medicines.

801Reports
56%Marked serious
40%Recovered
5.0%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
354 57%
1–2 days
142 23%
3–7 days
52 8.4%
1–4 weeks
30 4.8%
Over a month
43 6.9%

How the animals did

Recovered
319 40%
Recovered with lasting effects
2 0.2%
Still unwell when reported
46 5.7%
Died
23 2.9%
Euthanised
17 2.1%
Not known
394 49%

Problems reported at the same time

Age of the animals

Under 1 year
154
1–3 years
245
4–7 years
174
8–11 years
92
12+ years
78

About this medicine

Emodepside treats intestinal worms (spot-on for cats). Praziquantel treats tapeworms.

Products with this combination include Profender. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Emodepside + Praziquantel cause vomiting in cats?
801 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vomiting with similar medicines

All reported side effects of Emodepside + Praziquantel in cats · Medicines most reported with vomiting