Vomiting after Febantel + Praziquantel + Pyrantel (Drontal Plus) in cats

30 reports to the FDA describe vomiting in cats given Febantel + Praziquantel + Pyrantel. That is 43% of all reports for this medicine, compared with 18% across reports for all cat medicines, so it is reported unusually often with this medicine.

30Reports
37%Marked serious
40%Recovered
3.3%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
14 82%
1–2 days
3 18%
3–7 days
0 0.0%
1–4 weeks
0 0.0%
Over a month
0 0.0%

How the animals did

Recovered
12 40%
Still unwell when reported
2 6.7%
Died
1 3.3%
Not known
15 50%

Problems reported at the same time

Lethargy
11 37%
Drooling
6 20%
Diarrhea
4 13%
Wobbliness (ataxia)
3 10%
Drug administration error
3 10%
Restlessness or agitation
2 6.7%
Eye or vision problems
2 6.7%

Age of the animals

Under 1 year
6
1–3 years
7
4–7 years
7
8–11 years
2
12+ years
2

About this medicine

Febantel treats intestinal worms. Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Products with this combination include Drontal Plus. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Febantel + Praziquantel + Pyrantel cause vomiting in cats?
30 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vomiting with similar medicines

All reported side effects of Febantel + Praziquantel + Pyrantel in cats · Medicines most reported with vomiting