Vomiting after Praziquantel + Pyrantel in cats

408 reports to the FDA describe vomiting in cats given Praziquantel + Pyrantel. That is 32% of all reports for this medicine, compared with 18% across reports for all cat medicines, so it is reported unusually often with this medicine.

408Reports
41%Marked serious
61%Recovered
4.2%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
221 71%
1–2 days
44 14%
3–7 days
21 6.8%
1–4 weeks
11 3.5%
Over a month
14 4.5%

How the animals did

Recovered
248 61%
Recovered with lasting effects
2 0.5%
Still unwell when reported
17 4.2%
Died
13 3.2%
Euthanised
4 1.0%
Not known
124 30%

Problems reported at the same time

Age of the animals

Under 1 year
82
1–3 years
98
4–7 years
67
8–11 years
68
12+ years
52

About this medicine

Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Praziquantel + Pyrantel cause vomiting in cats?
408 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Vomiting with similar medicines

All reported side effects of Praziquantel + Pyrantel in cats · Medicines most reported with vomiting