Diarrhea after Praziquantel + Pyrantel in cats

85 reports to the FDA describe diarrhea in cats given Praziquantel + Pyrantel. That is 6.7% of all reports for this medicine, compared with 5.1% across reports for all cat medicines.

85Reports

49%Marked serious

29%Recovered

8.2%Died or euthanised

1 daysTypical onset

How soon it started

Same day

15 23%

1–2 days

26 39%

3–7 days

11 17%

1–4 weeks

7 11%

Over a month

7 11%

How the animals did

Recovered

24 28%

Recovered with lasting effects

1 1.2%

Still unwell when reported

10 12%

Died

3 3.5%

Euthanised

4 4.7%

Not known

43 51%

Problems reported at the same time

35 41%

23 27%

17 20%

10 12%

10 12%

7 8.2%

Didn't work as expected

7 8.2%

Behaviour change

6 7.1%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Questions owners ask

Can Praziquantel + Pyrantel cause diarrhea in cats?: 85 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 1 day of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Diarrhea with similar medicines

Diarrhea after Emodepside + Praziquantel (Profender) 238 reports · 4.2% of its reports
Diarrhea after Praziquantel 135 reports · 8.1% of its reports
Diarrhea after Pyrantel 70 reports · 13% of its reports
Diarrhea after Fenbendazole 34 reports · 12% of its reports

All reported side effects of Praziquantel + Pyrantel in cats · Medicines most reported with diarrhea