Didn't work as expected after Emodepside + Praziquantel (Profender) in cats

46 reports to the FDA describe didn't work as expected in cats given Emodepside + Praziquantel. That is 0.8% of all reports for this medicine, compared with 8.7% across reports for all cat medicines, so it is reported less often than average with this medicine.

46Reports
46%Marked serious
22%Recovered
4.3%Died or euthanised
18 daysTypical onset
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How soon it started

Same day
2 6.7%
1–2 days
2 6.7%
3–7 days
5 17%
1–4 weeks
10 33%
Over a month
11 37%

How the animals did

Recovered
10 22%
Still unwell when reported
3 6.5%
Died
1 2.2%
Euthanised
1 2.2%
Not known
31 67%

Problems reported at the same time

11 24%
4 8.7%
3 6.5%
Drug dose administration interval too long
3 6.5%

Age of the animals

Under 1 year
12
1–3 years
14
4–7 years
6
8–11 years
4
12+ years
4

About this medicine

Emodepside treats intestinal worms (spot-on for cats). Praziquantel treats tapeworms.

Products with this combination include Profender. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Emodepside + Praziquantel cause didn't work as expected in cats?
46 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 18 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

All reported side effects of Emodepside + Praziquantel in cats · Medicines most reported with didn't work as expected