Overdose after Emodepside + Praziquantel (Profender) in cats

83 reports to the FDA describe overdose in cats given Emodepside + Praziquantel. That is 1.4% of all reports for this medicine, compared with 0.9% across reports for all cat medicines, so it is reported unusually often with this medicine.

83Reports
45%Marked serious
30%Recovered
2.4%Died or euthanised
1 daysTypical onset
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How soon it started

Same day
21 40%
1–2 days
11 21%
3–7 days
8 15%
1–4 weeks
11 21%
Over a month
1 1.9%

How the animals did

Recovered
25 30%
Still unwell when reported
2 2.4%
Died
1 1.2%
Euthanised
1 1.2%
Not known
54 65%

Problems reported at the same time

Age of the animals

Under 1 year
26
1–3 years
33
4–7 years
9
8–11 years
8
12+ years
4

About this medicine

Emodepside treats intestinal worms (spot-on for cats). Praziquantel treats tapeworms.

Products with this combination include Profender. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Emodepside + Praziquantel cause overdose in cats?
83 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 1 day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Overdose with similar medicines

All reported side effects of Emodepside + Praziquantel in cats · Medicines most reported with overdose