Grapiprant (Galliprant) side effects in dogs

8,780 reports sent to the FDA between 2013 and 2026 involve Grapiprant in dogs. The most reported problems were vomiting, diarrhea, loss of appetite. 34% were marked serious, and where it was recorded, signs eased after stopping the medicine in 92% of cases.

8,780Reports
34%Marked serious
33%Only medicine involved
21%Recovered
11%Died or euthanised
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About this medicine

Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).

Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Most reported side effects

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a dog still getting fleas or heartworm), not about a side effect.

Didn't prevent heartworm
19 0.2%
Didn't stop ticks
5 0.1%

How soon problems started

Same day
1,415 21%
1–2 days
750 11%
3–7 days
728 11%
1–4 weeks
1,102 16%
Over a month
2,892 42%

Time from the first dose to the first sign, where both dates were reported (6,887 reports).

How the animals did

Recovered
1,846 21%
Recovered with lasting effects
41 0.5%
Still unwell when reported
3,201 36%
Died
334 3.8%
Euthanised
644 7.3%
Not known
2,714 31%

Breeds named most often

Popular breeds appear more often because there are more of them.

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