Didn't stop fleas after Grapiprant (Galliprant) in dogs

The FDA has received 21 reports of didn't stop fleas in dogs after Grapiprant. That is 0.2% of all reports for this medicine, compared with 6.2% across reports for all dog medicines, so it is reported less often than average with this medicine.

21Reports

9.5%Marked serious

9.5%Recovered

0.0%Died or euthanised

–Typical onset

How the animals did

Recovered

2 9.5%

Still unwell when reported

1 4.8%

Not known

18 86%

Problems reported at the same time

Itching

2 9.5%

Arthritis

1 4.8%

Liver disorder

1 4.8%

Ringworm

1 4.8%

Underdose

1 4.8%

Cushings disease

1 4.8%

Seizures

1 4.8%

Defect unknown/not specified

1 4.8%

Age of the animals

Under 1 year

1–3 years

4–7 years

8–11 years

12+ years

About this medicine

Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).

Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Grapiprant cause didn't stop fleas in dogs?: 21 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't stop fleas with similar medicines

Didn't stop fleas after Carprofen (Rimadyl) 59 reports · 0.1% of its reports
Didn't stop fleas after Meloxicam (Metacam) 22 reports · 0.3% of its reports

All reported side effects of Grapiprant in dogs · Medicines most reported with didn't stop fleas