Blood problems after Grapiprant (Galliprant) in dogs

The FDA has received 368 reports of blood problems in dogs after Grapiprant. That is 4.2% of all reports for this medicine, compared with 1.8% across reports for all dog medicines, so it is reported unusually often with this medicine.

368Reports
79%Marked serious
7.6%Recovered
31%Died or euthanised
36 daysTypical onset
SponsoredWorried about your pet? Ask a veterinarian online, 24/7

How soon it started

Same day
19 7.3%
1–2 days
17 6.5%
3–7 days
34 13%
1–4 weeks
46 18%
Over a month
144 55%

How the animals did

Recovered
25 6.8%
Recovered with lasting effects
3 0.8%
Still unwell when reported
170 46%
Died
22 6.0%
Euthanised
91 25%
Not known
57 15%

Problems reported at the same time

Age of the animals

Under 1 year
5
1–3 years
11
4–7 years
33
8–11 years
148
12+ years
166

About this medicine

Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).

Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Grapiprant cause blood problems in dogs?
368 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 36 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Blood problems with similar medicines

All reported side effects of Grapiprant in dogs · Medicines most reported with blood problems