Liver problems after Grapiprant (Galliprant) in dogs
1,142 reports to the FDA describe liver problems in dogs given Grapiprant. That is 13% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.
1,142Reports
48%Marked serious
6.0%Recovered
15%Died or euthanised
37 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).
Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.
Questions owners ask
- Can Grapiprant cause liver problems in dogs?
- 1,142 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 37 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Liver problems with similar medicines
- Liver problems after Carprofen (Rimadyl) 13,930 reports · 29% of its reports
- Liver problems after Deracoxib (Deramaxx) 2,455 reports · 22% of its reports
- Liver problems after Meloxicam (Metacam) 1,035 reports · 13% of its reports
- Liver problems after Firocoxib (Previcox) 1,344 reports · 17% of its reports
All reported side effects of Grapiprant in dogs · Medicines most reported with liver problems