Liver problems after Firocoxib (Previcox) in dogs

1,344 reports to the FDA describe liver problems in dogs given Firocoxib. That is 17% of all reports for this medicine, compared with 4.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

1,344Reports
31%Marked serious
5.3%Recovered
25%Died or euthanised
14 daysTypical onset
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How soon it started

Same day
33 7.8%
1–2 days
48 11%
3–7 days
92 22%
1–4 weeks
99 23%
Over a month
152 36%

How the animals did

Recovered
61 4.5%
Recovered with lasting effects
10 0.7%
Still unwell when reported
116 8.6%
Died
267 20%
Euthanised
69 5.1%
Not known
821 61%

Problems reported at the same time

Age of the animals

Under 1 year
18
1–3 years
90
4–7 years
241
8–11 years
578
12+ years
388

About this medicine

Firocoxib relieves pain and inflammation from arthritis.

Products with this ingredient include Previcox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Firocoxib cause liver problems in dogs?
1,344 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 14 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Liver problems with similar medicines

All reported side effects of Firocoxib in dogs · Medicines most reported with liver problems