Leucocytosis after Firocoxib (Previcox) in dogs

338 reports to the FDA describe leucocytosis in dogs given Firocoxib. That is 4.2% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

338Reports
43%Marked serious
9.8%Recovered
37%Died or euthanised
6 daysTypical onset
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How soon it started

Same day
11 7.4%
1–2 days
19 13%
3–7 days
53 36%
1–4 weeks
36 24%
Over a month
29 20%

How the animals did

Recovered
31 9.2%
Recovered with lasting effects
2 0.6%
Still unwell when reported
42 12%
Died
100 30%
Euthanised
24 7.1%
Not known
139 41%

Problems reported at the same time

Age of the animals

Under 1 year
10
1–3 years
42
4–7 years
83
8–11 years
137
12+ years
64

About this medicine

Firocoxib relieves pain and inflammation from arthritis.

Products with this ingredient include Previcox. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Firocoxib cause leucocytosis in dogs?
338 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 6 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Leucocytosis with similar medicines

All reported side effects of Firocoxib in dogs · Medicines most reported with leucocytosis