Leucocytosis after Carprofen (Rimadyl) in dogs

2,582 reports to the FDA describe leucocytosis in dogs given Carprofen. That is 5.5% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

2,582Reports

22%Marked serious

2.8%Recovered

43%Died or euthanised

6 daysTypical onset

How soon it started

Same day

89 13%

1–2 days

117 17%

3–7 days

168 25%

1–4 weeks

177 26%

Over a month

127 19%

How the animals did

Recovered

67 2.6%

Recovered with lasting effects

6 0.2%

Still unwell when reported

324 13%

Died

896 35%

Euthanised

212 8.2%

Not known

1,077 42%

Problems reported at the same time

1,785 69%

1,472 57%

1,332 52%

1,187 46%

1,110 43%

1,074 42%

966 37%

630 24%

Age of the animals

Under 1 year

112

1–3 years

254

4–7 years

666

8–11 years

1,000

12+ years

536

About this medicine

Carprofen relieves pain and inflammation from arthritis or after surgery.

Products with this ingredient include Rimadyl, Novox, Vetprofen. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Carprofen cause leucocytosis in dogs?: 2,582 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?: In half of the reports with dates, it started within 6 days of the first dose.
What should I do?: Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Leucocytosis with similar medicines

Leucocytosis after Deracoxib (Deramaxx) 774 reports · 7.0% of its reports
Leucocytosis after Grapiprant (Galliprant) 151 reports · 1.7% of its reports
Leucocytosis after Meloxicam (Metacam) 279 reports · 3.5% of its reports
Leucocytosis after Firocoxib (Previcox) 338 reports · 4.2% of its reports

All reported side effects of Carprofen in dogs · Medicines most reported with leucocytosis