Didn't work as expected after Grapiprant (Galliprant) in dogs

The FDA has received 1,360 reports of didn't work as expected in dogs after Grapiprant. That is 15% of all reports for this medicine, compared with 13% across reports for all dog medicines.

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How soon it started

How the animals did

Problems reported at the same time

Age of the animals

About this medicine

Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).

Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Grapiprant cause didn't work as expected in dogs?

1,360 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.

How soon after a dose was it reported?

In half of the reports with dates, it started within 31 days of the first dose.

What should I do?

Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Didn't work as expected with similar medicines

• Didn't work as expected after Carprofen (Rimadyl) 2,515 reports · 5.3% of its reports
• Didn't work as expected after Deracoxib (Deramaxx) 381 reports · 3.5% of its reports
• Didn't work as expected after Meloxicam (Metacam) 428 reports · 5.3% of its reports
• Didn't work as expected after Firocoxib (Previcox) 441 reports · 5.5% of its reports

All reported side effects of Grapiprant in dogs · Medicines most reported with didn't work as expected