Weight loss after Grapiprant (Galliprant) in dogs

395 reports to the FDA describe weight loss in dogs given Grapiprant. That is 4.5% of all reports for this medicine, compared with 1.7% across reports for all dog medicines, so it is reported unusually often with this medicine.

395Reports
62%Marked serious
9.4%Recovered
21%Died or euthanised
29 daysTypical onset
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How soon it started

Same day
41 15%
1–2 days
26 9.6%
3–7 days
29 11%
1–4 weeks
45 17%
Over a month
131 48%

How the animals did

Recovered
36 9.1%
Recovered with lasting effects
1 0.3%
Still unwell when reported
180 46%
Died
12 3.0%
Euthanised
72 18%
Not known
94 24%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
10
4–7 years
30
8–11 years
129
12+ years
213

About this medicine

Grapiprant relieves arthritis pain (a piprant, a newer non-COX NSAID).

Products with this ingredient include Galliprant. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

NSAIDs can affect the stomach, liver and kidneys. Vets usually recommend blood tests before and during long-term use.

Questions owners ask

Can Grapiprant cause weight loss in dogs?
395 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 29 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Weight loss with similar medicines

All reported side effects of Grapiprant in dogs · Medicines most reported with weight loss