Neutrophilia after Polysulfated Glycosaminoglycan in dogs

The FDA has received 89 reports of neutrophilia in dogs after Polysulfated Glycosaminoglycan. That is 1.6% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

89Reports
74%Marked serious
9.0%Recovered
34%Died or euthanised
19 daysTypical onset
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How soon it started

Same day
10 20%
1–2 days
5 10%
3–7 days
6 12%
1–4 weeks
12 24%
Over a month
16 33%

How the animals did

Recovered
8 9.0%
Still unwell when reported
19 21%
Died
13 15%
Euthanised
17 19%
Not known
32 36%

Problems reported at the same time

Age of the animals

Under 1 year
0
1–3 years
8
4–7 years
18
8–11 years
32
12+ years
31

About this medicine

Type: medicine.

Questions owners ask

Can Polysulfated Glycosaminoglycan cause neutrophilia in dogs?
89 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 19 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neutrophilia with similar medicines

All reported side effects of Polysulfated Glycosaminoglycan in dogs · Medicines most reported with neutrophilia