Neutrophilia after Butorphanol in dogs

The FDA has received 106 reports of neutrophilia in dogs after Butorphanol. That is 2.4% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

106Reports
73%Marked serious
14%Recovered
32%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
24 27%
1–2 days
18 20%
3–7 days
10 11%
1–4 weeks
16 18%
Over a month
21 24%

How the animals did

Recovered
14 13%
Recovered with lasting effects
1 0.9%
Still unwell when reported
36 34%
Died
14 13%
Euthanised
20 19%
Not known
21 20%

Problems reported at the same time

Age of the animals

Under 1 year
11
1–3 years
17
4–7 years
23
8–11 years
43
12+ years
12

About this medicine

Type: medicine.

Questions owners ask

Can Butorphanol cause neutrophilia in dogs?
106 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neutrophilia with similar medicines

All reported side effects of Butorphanol in dogs · Medicines most reported with neutrophilia