Neutrophilia after Desoxycorticosterone Pivalate in dogs

60 reports to the FDA describe neutrophilia in dogs given Desoxycorticosterone Pivalate. That is 1.8% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

60Reports
67%Marked serious
3.3%Recovered
12%Died or euthanised
35 daysTypical onset
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How soon it started

Same day
0 0.0%
1–2 days
3 12%
3–7 days
2 7.7%
1–4 weeks
7 27%
Over a month
14 54%

How the animals did

Recovered
2 3.3%
Still unwell when reported
14 23%
Died
4 6.7%
Euthanised
3 5.0%
Not known
37 62%

Problems reported at the same time

22 37%
18 30%
Monocytosis
16 27%

Age of the animals

Under 1 year
0
1–3 years
9
4–7 years
23
8–11 years
16
12+ years
11

About this medicine

Type: medicine.

Questions owners ask

Can Desoxycorticosterone Pivalate cause neutrophilia in dogs?
60 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 35 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neutrophilia with similar medicines

All reported side effects of Desoxycorticosterone Pivalate in dogs · Medicines most reported with neutrophilia