Neutrophilia after Tramadol in dogs

The FDA has received 129 reports of neutrophilia in dogs after Tramadol. That is 3.4% of all reports for this medicine, compared with 0.6% across reports for all dog medicines, so it is reported unusually often with this medicine.

129Reports
76%Marked serious
9.3%Recovered
40%Died or euthanised
4 daysTypical onset
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How soon it started

Same day
12 12%
1–2 days
26 27%
3–7 days
16 16%
1–4 weeks
22 23%
Over a month
21 22%

How the animals did

Recovered
11 8.5%
Recovered with lasting effects
1 0.8%
Still unwell when reported
48 37%
Died
16 12%
Euthanised
35 27%
Not known
18 14%

Problems reported at the same time

Age of the animals

Under 1 year
2
1–3 years
17
4–7 years
43
8–11 years
42
12+ years
24

About this medicine

Type: medicine.

Questions owners ask

Can Tramadol cause neutrophilia in dogs?
129 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 4 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Neutrophilia with similar medicines

All reported side effects of Tramadol in dogs · Medicines most reported with neutrophilia