Eprinomectin + Praziquantel side effects in cats

585 reports sent to the FDA between 2018 and 2026 involve Eprinomectin + Praziquantel in cats. The most reported problems were drooling, vomiting, lethargy. 11% were marked serious.

585Reports
11%Marked serious
85%Only medicine involved
28%Recovered
5.1%Died or euthanised
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About this medicine

Eprinomectin controls worms and prevents heartworm. Praziquantel treats tapeworms.

Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.

Most reported side effects

Share = percentage of this medicine's reports that mention the problem. One report can list several problems.

Reports that it didn't work

Some reports are about the medicine not working (for example a cat still getting fleas or heartworm), not about a side effect.

Didn't work as expected
5 0.9%
Didn't stop fleas
2 0.3%

How soon problems started

Same day
301 52%
1–2 days
120 21%
3–7 days
53 9.2%
1–4 weeks
72 13%
Over a month
28 4.9%

Time from the first dose to the first sign, where both dates were reported (574 reports).

How the animals did

Recovered
164 28%
Still unwell when reported
24 4.1%
Died
17 2.9%
Euthanised
13 2.2%
Not known
367 63%

Breeds named most often

Popular breeds appear more often because there are more of them.

Other macrocyclic lactone (heartworm and parasite prevention)s for cats