Hair loss after Eprinomectin + Praziquantel in cats

54 reports to the FDA describe hair loss in cats given Eprinomectin + Praziquantel. That is 9.2% of all reports for this medicine, compared with 14% across reports for all cat medicines, so it is reported less often than average with this medicine.

54Reports
1.9%Marked serious
11%Recovered
0.0%Died or euthanised
2 daysTypical onset
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How soon it started

Same day
5 9.4%
1–2 days
22 42%
3–7 days
17 32%
1–4 weeks
8 15%
Over a month
1 1.9%

How the animals did

Recovered
6 11%
Still unwell when reported
3 5.6%
Not known
45 83%

Problems reported at the same time

13 24%
Skin scab
2 3.7%
2 3.7%
Vocalising
1 1.9%
Skin disorders
1 1.9%
1 1.9%

Age of the animals

Under 1 year
4
1–3 years
14
4–7 years
13
8–11 years
14
12+ years
8

About this medicine

Eprinomectin controls worms and prevents heartworm. Praziquantel treats tapeworms.

Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.

Questions owners ask

Can Eprinomectin + Praziquantel cause hair loss in cats?
54 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within 2 days of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Hair loss with similar medicines

All reported side effects of Eprinomectin + Praziquantel in cats · Medicines most reported with hair loss