Foaming at the mouth after Eprinomectin + Praziquantel in cats
The FDA has received 60 reports of foaming at the mouth in cats after Eprinomectin + Praziquantel. That is 10% of all reports for this medicine, compared with 1.3% across reports for all cat medicines, so it is reported unusually often with this medicine.
60Reports
8.3%Marked serious
43%Recovered
5.0%Died or euthanised
Same dayTypical onset
Sponsored
How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Eprinomectin controls worms and prevents heartworm. Praziquantel treats tapeworms.
Some herding breeds (for example Collies) carry the MDR1 gene variant and can be more sensitive to this drug class at high doses.
Questions owners ask
- Can Eprinomectin + Praziquantel cause foaming at the mouth in cats?
- 60 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within the same day of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Foaming at the mouth with similar medicines
- Foaming at the mouth after Selamectin (Revolution) 56 reports · 0.3% of its reports
- Foaming at the mouth after Eprinomectin + Esafoxolaner + Praziquantel (NexGard Combo) 255 reports · 7.9% of its reports
All reported side effects of Eprinomectin + Praziquantel in cats · Medicines most reported with foaming at the mouth