Underdose after Pyrantel + Sarolaner (Simparica Trio) in dogs
216 reports to the FDA describe underdose in dogs given Pyrantel + Sarolaner. That is 0.4% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported less often than average with this medicine.
216Reports
61%Marked serious
13%Recovered
2.3%Died or euthanised
15 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Pyrantel treats roundworms and hookworms. Sarolaner kills fleas, ticks and some mites; monthly.
Products with this combination include Simparica Trio (which also contains moxidectin). The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Pyrantel + Sarolaner cause underdose in dogs?
- 216 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 15 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Underdose with similar medicines
- Underdose after Febantel + Praziquantel + Pyrantel (Drontal Plus) 247 reports · 3.7% of its reports
- Underdose after Fenbendazole 229 reports · 3.9% of its reports
- Underdose after Pyrantel 82 reports · 1.7% of its reports
- Underdose after Praziquantel + Pyrantel 65 reports · 1.8% of its reports
- Underdose after Praziquantel 28 reports · 2.5% of its reports
All reported side effects of Pyrantel + Sarolaner in dogs · Medicines most reported with underdose