Intentional misuse after Pyrantel + Sarolaner (Simparica Trio) in dogs
The FDA has received 1,951 reports of intentional misuse in dogs after Pyrantel + Sarolaner. That is 3.7% of all reports for this medicine, compared with 0.4% across reports for all dog medicines, so it is reported unusually often with this medicine.
1,951Reports
57%Marked serious
3.1%Recovered
0.6%Died or euthanised
88 daysTypical onset
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How soon it started
How the animals did
Problems reported at the same time
Age of the animals
About this medicine
Pyrantel treats roundworms and hookworms. Sarolaner kills fleas, ticks and some mites; monthly.
Products with this combination include Simparica Trio (which also contains moxidectin). The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.
Questions owners ask
- Can Pyrantel + Sarolaner cause intentional misuse in dogs?
- 1,951 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
- How soon after a dose was it reported?
- In half of the reports with dates, it started within 88 days of the first dose.
- What should I do?
- Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).
Intentional misuse with similar medicines
- Intentional misuse after Fenbendazole 23 reports · 0.4% of its reports
All reported side effects of Pyrantel + Sarolaner in dogs · Medicines most reported with intentional misuse