Underdose after Febantel + Praziquantel + Pyrantel (Drontal Plus) in dogs

247 reports to the FDA describe underdose in dogs given Febantel + Praziquantel + Pyrantel. That is 3.7% of all reports for this medicine, compared with 1.0% across reports for all dog medicines, so it is reported unusually often with this medicine.

247Reports
30%Marked serious
38%Recovered
3.2%Died or euthanised
Same dayTypical onset
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How soon it started

Same day
91 54%
1–2 days
28 17%
3–7 days
13 7.7%
1–4 weeks
20 12%
Over a month
17 10%

How the animals did

Recovered
95 38%
Still unwell when reported
15 6.1%
Died
6 2.4%
Euthanised
2 0.8%
Not known
129 52%

Problems reported at the same time

Age of the animals

Under 1 year
104
1–3 years
62
4–7 years
33
8–11 years
20
12+ years
19

About this medicine

Febantel treats intestinal worms. Praziquantel treats tapeworms. Pyrantel treats roundworms and hookworms.

Products with this combination include Drontal Plus. The FDA hides brand names in its public data, so these reports cover every product with the same active ingredients.

Questions owners ask

Can Febantel + Praziquantel + Pyrantel cause underdose in dogs?
247 reports link the two, but a report alone does not prove the medicine was the cause: other illnesses, other medicines or coincidence can be involved. Your vet can judge it for your animal.
How soon after a dose was it reported?
In half of the reports with dates, it started within the same day of the first dose.
What should I do?
Don't give another dose until you've spoken to your vet, and keep the packaging so you can tell them the product and dose. Your vet can also report it to the FDA (or you can, through the manufacturer or FDA form 1932a).

Underdose with similar medicines

All reported side effects of Febantel + Praziquantel + Pyrantel in dogs · Medicines most reported with underdose